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Grey May: Advancing brain cancer research and treatment

Understanding the challenge 

Brain tumours such as glioblastoma (the most aggressive and common malignant adult brain tumour) are notoriously difficult to treat. One reason for this is the blood-brain barrier, a protective shield that prevents harmful substances from entering the brain. Unfortunately this barrier also blocks many chemotherapy drugs. Additionally, brain tumours are highly adaptive. They mutate quickly, making standard treatments like surgery, radiation and chemotherapy less effective over time. 

Australia’s brain cancer statistics show just how harmful this formidable disease is. In 2025, there were an estimated 2,098 new cases of brain cancer diagnosis and an estimated 1,639 deaths from brain cancer. After a diagnosis, there is only a 24% chance of surviving at least 5 years. Brain cancer is the ninth most common cause of cancer death in Australia. 

Despite these obstacles, brain cancer research is advancing in powerful ways. 

 

Medical advances 

Over the past decade, researchers and doctors have made important strides in how brain cancer is treated and understood. 

Targeted therapy 

In recent years, progress in brain cancer treatment has focussed on working smarter, not just harder. Instead of using only traditional chemotherapy, researchers are now studying each patient’s tumour more closely to understand its unique makeup. This allows them to choose treatments that are more personalised and potentially more effective. 

Evolving immunotherapy 

Immunotherapy has revolutionised treatment for several cancers, helping the body’s own immune system recognise and fight cancer cells. While this approach is still developing for brain tumours, early research and clinical trials are offering new possibilities for patients who previously had limited options. 

Improved surgery and radiation 

Surgery and radiation treatments have has become far more precise. Modern technology allows doctors to see and target tumours with pinpoint accuracy, helping protect healthy parts of the brain. This precision reduces side effects and improves quality of life during and after treatment. 

 

Be a champion for brain cancer awareness 

Grey May is more than a time to learn – it’s a time to act. While research is advancing, progress depends on continued funding, advocacy and public support.  

Airtrain is a proud partner of QIMR Berghofer Medical Research Institute, whose team of dedicated brain cancer researchers share our mission to find a cure for this devastating disease. By donating to QIMR Berghofer, you help fund innovative treatments and accelerate discovers that could change survival rates for future generations.  

One of the easiest ways you can show your support to raise brain cancer awareness this May is to make an online donation to help fund vital research. You can donate directly to QIMR Berghofer via the QIMR Berghofer website. Alternatively, when you book your Airtrain tickets online via our Booking Form you can tick the donation box. All donations go directly toward life-saving brain cancer research.